Why the study?
Does prostaglandin E1 preserve platelet numbers and function during in vitro simulation of cardiopulmonary bypass?
Does prostaglandin E1 preserve platelet numbers and function during in vitro simulation of cardiopulmonary bypass?
Prostaglandin E1 preserves platelet numbers and prevents contact-initiated release during in vitro extracorporeal bypass, suggesting a potential strategy to mitigate bypass-induced platelet abnormalities.
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PGE1 preserved platelets in this bypass model; leaves open whether it reduces clinical platelet dysfunction during cardiopulmonary bypass.
Addonizio et al. (1979) studied this question.
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