Why the study?
Does adenosine or Prostaglandin E1 prevent platelet loss during cardiopulmonary bypass and are they hemodynamically tolerated in a canine model?
Does adenosine or Prostaglandin E1 prevent platelet loss during cardiopulmonary bypass and are they hemodynamically tolerated in a canine model?
This preclinical study investigates the potential of adenosine and Prostaglandin E1 to prevent platelet loss during cardiopulmonary bypass.
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Hypothesis-generating in canines; leaves open translation to human CPB platelet preservation.
Masters et al. (1982) studied this question.
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