Key result
Obese children and those at risk for obesity demonstrated increased late diastolic myocardial motion and decreased systolic strain compared with normal-weight children.
Why the study?
Does obesity alter myocardial velocity, strain, and strain rate in children compared to normal-weight children?
Observational (n=168)
Does obesity alter myocardial velocity, strain, and strain rate in children compared to normal-weight children?
Obese children exhibit subclinical abnormalities in systolic strain and diastolic function, which may serve as early markers for future cardiac disease.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for early myocardial changes in obese youth; longitudinal studies needed before clinical relevance.
Childhood obesity is a major health care issue in the United States. This epidemic has important cardiovascular implications. Newer imaging modalities in obese adults have demonstrated abnormal systolic and diastolic cardiac function. The authors proposed to determine whether these abnormalities are present in obese children. A total of 168 children were identified from our echocardiographic database. Body mass index for age was calculated. Echocardiographic clips were analyzed using imaging technology to determine myocardial motion, strain, and strain rate. Patients at risk for obesity and those meeting criteria for obesity had increased late diastolic myocardial motion compared with normal-weight children. Obese patients had decreased systolic strain compared with normal-weight children. As with adults, obese children have significant differences in diastolic function and strain. These abnormalities may be subtle markers for the emergence of future cardiac disease.
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Lorch et al. (2007) conducted an observational in Childhood obesity (n=168). Obesity vs. Normal-weight children was evaluated on Myocardial motion, strain, and strain rate. Obese children and those at risk for obesity demonstrated increased late diastolic myocardial motion and decreased systolic strain compared with normal-weight children.
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