September 1, 1998Journal of Cardiovascular Electrophysiology

Virtual Electrode Effects in Transvenous Defibrillation‐Modulation by Structure and Interface: Evidence from Bidomain Simulations and Optical Mapping

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Population

Langendorff-perfused rabbit hearts (n = 4) stained with di-4-ANEPPS and an ellipsoidal bidomain heart model

Comparison

Monophasic shocks applied during the plateau… vs Varying interface conditions

Design

Preclinical

Authors

EEEmilia EntchevaGeorge Washington University JEJames EasonUniversity of Memphis IEIgor R. EfimovElectrophysiology

Discussion

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Implication

Anisotropy must inform defibrillation models; extends simulation-experiment linkage but leaves open clinical translation.

Structured PICO

Population

Langendorff-perfused rabbit hearts (n = 4) stained with di-4-ANEPPS and an ellipsoidal bidomain heart model

Intervention

Monophasic shocks applied during the plateau phase of an action potential through a 9-mm long distal electrode in the right or left ventricle and a 6-cm proximal electrode positioned 3 cm posteriorly

Comparator

Varying interface conditions (tissue bath conditions and anisotropy ratios)

Outcome

Presence and characteristics of virtual electrode effects (VEE) and epicardial polarization patternssurrogate

Virtual electrode effects are present during transvenous defibrillation and are shaped by cardiac tissue characteristics and interface conditions, potentially impacting defibrillation outcomes.

Cite This Study

Entcheva et al. (1998) studied this question.

synapsesocial.com/papers/6a74e291f5fc394144033ccb https://doi.org/10.1111/j.1540-8167.1998.tb00135.x

Topics

Cardiac device therapy

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Virtual Electrode Effects in Transvenous Defibrillation‐Modulation by Structure and Interface: Evidence from Bidomain Simulations and Optical Mapping

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Virtual Electrode Effects in Transvenous Defibrillation‐Modulation by Structure and Interface: Evidence from Bidomain Simulations and Optical Mapping

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider