Why the study?
Does the addition of inorganic phosphate affect loaded shortening and power output in rat skinned cardiac myocytes?
Does the addition of inorganic phosphate affect loaded shortening and power output in rat skinned cardiac myocytes?
Inorganic phosphate release is a rate-limiting step for determining shortening velocity and power output at intermediate and high relative loads in cardiac myocytes.
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Pi may modulate myocyte power independently of force; hypothesis-generating in rats and leaves open human translation.
Hinken et al. (2004) studied this question.