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January 1, 1991AJP Heart and Circulatory Physiology

Impaired myocardial function in spontaneously hypertensive rats with heart failure

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Authors

CCChester H. ConradSt. Elizabeth's Medical Center WBWesley W. BrooksBoston University KRKathleen G. RobinsonBoston University

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Implication

Supports intrinsic LV contractile impairment in end-stage hypertensive rat HF; leaves open translation to human phenotypes and therapies.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Conrad et al. (1991) studied this question.

synapsesocial.com/papers/6a751cdaa44b96c1f7dbeee8 https://doi.org/10.1152/ajpheart.1991.260.1.h136

Topics

Hypertension management

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1The spontaneously hypertensive rat as a model of the transition from compensated left ventricular hypertrophy to failure1995 · 214 citations
2Increased cardiac work provides a link between systemic hypertension and heart failure2017 · 15 citations
3Increased Systolic Performance With Diastolic Dysfunction in Adult Spontaneously Hypertensive Rats2003 · 124 citations
4Old spontaneously hypertensive rats gather together typical features of human chronic left-ventricular dysfunction with preserved ejection fraction2014 · 20 citations
5Cardiac function and morphology with aging in the spontaneously hypertensive rat1979 · 231 citations