Why the study?
Does everyday exercise alter steady-state plasma digoxin concentrations in older men?
Population
18 men age 50-85 years treated with digoxin for more than 1 month before enrolling, with baseline serum…
Comparison
Sequential 60-minute periods of rest, walking… vs Rest phases compared to the walking phase.
Design
Cohort
Follow-up
3 hours
Authors
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Supports no effect of routine walking on digoxin levels in older men; hypothesis-generating and should not yet change practice.
Does everyday exercise alter steady-state plasma digoxin concentrations in older men?
Everyday exercise has minimal, if any, clinically relevant effects on steady-state plasma digoxin concentrations in older men.
Teague et al. (1995) studied this question.
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