Why the study?
Is the ACE insertion/deletion polymorphism associated with bone mineral density in hypertensive postmenopausal women?
Population
Hypertensive postmenopausal women
Comparison
Angiotensin converting enzyme insertion/deletion… vs ACE ID and homozygotus deletion genotypes
Design
Cross-sectional
Authors
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Does not support changing practice based on ACE genotype; leaves open its utility for fracture risk stratification in hypertensive women.
Is the ACE insertion/deletion polymorphism associated with bone mineral density in hypertensive postmenopausal women?
The ACE II genotype is associated with higher intact parathyroid hormone levels and greater bone mineral density in hypertensive postmenopausal women compared to ID and deletion genotypes.
José Luis Pérez‐Castrillón (2003) studied this question.
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