Population
Human plasma and cerebrospinal fluid samples from normal subjects and patients with high renin levels
Comparison
Direct radioimmunoassay using polyclonal… vs Indirect assay measuring angiotensinogen through…
Design
Other
Authors
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Direct assay may be needed in high-renin states; leaves open clinical impact of des-angiotensin I-angiotensinogen detection.
A direct RIA for human angiotensinogen detects des-angiotensin I-angiotensinogen accumulation in high-renin states, which is missed by traditional indirect assays.
Genain et al. (1984) studied this question.
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