Why the study?
Is the VNTR polymorphism in intron 4 of the ecNOS gene associated with essential hypertension in Japanese subjects?
Population
243 Japanese subjects, comprising 123 individuals with essential hypertension and 120 normotensive control…
Comparison
Presence of the four-repeat allele in the… vs Normotensive control subjects.
Design
Case-control
Authors
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Should not change hypertension management; leaves open confirmation of ecNOS four-repeat allele as risk marker in Japanese subjects.
Is the VNTR polymorphism in intron 4 of the ecNOS gene associated with essential hypertension in Japanese subjects?
The four-repeat allele of the ecNOS gene is associated with essential hypertension and may serve as a genetic marker for the disease in Japanese subjects.
J. Uwabo (1998) studied this question.
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