Why the study?
Do normal plasma lipoproteins inhibit stimulated human lymphocyte proliferation?
Population
Human peripheral blood lymphocytes stimulated by allogeneic cells and lectins
Design
Preclinical
Authors
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Should not change clinical practice; leaves open an immunomodulatory role for lipoproteins in vivo.
Do normal plasma lipoproteins inhibit stimulated human lymphocyte proliferation?
Normal plasma lipoproteins potently inhibit lymphocyte proliferation in vitro, suggesting a potential immunomodulatory role for endogenous lipoproteins in vivo.
Morse et al. (1977) studied this question.
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