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September 14, 2009Circulation

Mitral Repair versus Replacement for Ischemic Mitral Regurgitation

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Why the study?

Does mitral valve repair improve survival compared to mitral valve replacement in patients with ischemic mitral regurgitation?

Population

370 patients with ischemic mitral regurgitation who underwent mitral valve surgery

Comparison

Mitral valve repair (MVRp) vs Mitral valve replacement (MVR)

Design

Cohort

Follow-up

6 years

Authors

JMJulien MagnéCardiac Imaging
Nicolas Girerd
Nicolas GirerdHeart Failure / Cardiomyopathy
MSMario SénéchalCegep de Sainte Foy

Discussion

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Implication

Repair was not associated with lower mortality than replacement in ischemic MR; leaves open optimal strategy pending randomized data.

Structured PICO

Does mitral valve repair improve survival compared to mitral valve replacement in patients with ischemic mitral regurgitation?

P
Population
370 patients with ischemic mitral regurgitation who underwent mitral valve surgery
I
Intervention
Mitral valve repair (MVRp)
C
Comparator
Mitral valve replacement (MVR)
O
Outcome
Operative mortality and overall 6-year survivalhard clinical

Mitral valve repair does not appear superior to replacement for operative or overall mortality in patients with ischemic mitral regurgitation, contrasting with findings in organic mitral regurgitation.

Cite This Study

Magné et al. (2009) studied this question.

synapsesocial.com/papers/6a7579f4f2cd31a1fadc1508https://doi.org/10.1161/circulationaha.108.843995

Topics

Mitral valve interventionWomen and heart disease
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mitral Repair Is Superior to Replacement When Associated With Coronary Artery Disease2004 · 93 citations
  2. 2The effect of pathophysiology on the surgical treatment of ischemic mitral regurgitation: operative and late risks of repair versus replacement1995 · 206 citations
  3. 3Late Results of Isolated Mitral Annuloplasty for "Functional" Ischemic Mitral Insufficiency2001 · 57 citations
  4. 4Mitral Regurgitation2003 · 110 citations
  5. 5Preoperative Posterior Leaflet Angle Accurately Predicts Outcome After Restrictive Mitral Valve Annuloplasty for Ischemic Mitral Regurgitation2007 · 269 citations