Correlation between cardio ankle vascular index, body mass index and pressure parameters in normal and overweight/obesity subjects

Background: Obesity and overweight are a risk factors and related to the arteriosclerosis mechanism. However, it has not been fully elucidated whether cardio ankle vascular index (CAVI) is closely associated with body mass index (BMI) and pressure parameters. Objectives: This study aimed to compare CAVI and BMI with normal weight and overweight/obesity group, and to investigate the correlation between CAVI, ankle brachial index (ABI), BMI and pressure parameters. Materials and methods: One hundred and twenty-four participants were divided into normal weight group (n=52), aged 47±12 years and overweight/obesity group (n=72), aged 48.50±13 years. Both CAVI and ABI were measured with a VaSera VS-1500N®; blood pressures were measured with an Omron M7®. Results: Average ABI and mean arterial pressure (MAP) of overweight/obesity group was higher than the normal weight group. In the univariable analysis, there was a significant negative correlation between BMI and the average CAVI (r=-0.194; p=0.031), and the association between the average CAVI and ABI were positively significant (r=0.225, p=0.012). Using a multivariate regression analysis, the average CAVI was negatively associated with BMI (β=-0.217, p=0.014), while the association between the average CAVI and ABI was positively correlated (β=0.246, p=0.005). Conclusion: The average CAVI and BMI were negatively correlated, while the average CAVI and average ABI were positively related. Using a multivariate regression analysis, the average CAVI is strongly associated with the average ABI and BMI.