Population
Preclinical model (specific animal not stated in abstract)
Comparison
Progressive increases in renal venous pressure… vs Baseline/control conditions
Design
Preclinical
Follow-up
Acute experiment (60-min infusion)
Authors
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Suggests angiotensin II preserves GFR during high renal venous pressure in this model; hypothesis-generating for human cardiorenal syndromes.
The renin-angiotensin system plays a crucial role in maintaining glomerular filtration rate during elevated renal venous pressure.
Kastner et al. (1982) studied this question.
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