Why the study?
Does adding prazosin to beta-blockers and diuretics reduce blood pressure in hypertensive patients with inadequate control?
Population
20 hypertensive patients with inadequate blood pressure control on beta-adrenoceptor blocking drugs and…
Design
Cohort, open study
Follow-up
12 weeks
Authors
Loading...
May support prazosin add-on in resistant hypertension on standard therapy; leaves open causal confirmation in RCTs.
Does adding prazosin to beta-blockers and diuretics reduce blood pressure in hypertensive patients with inadequate control?
Adding prazosin to beta-blockers and diuretics significantly reduces resting blood pressure in patients with inadequately controlled hypertension, though it is associated with weight gain.
Annika Wærn (1980) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: