What is the clinical evidence from this study?

Study design: Case Report. Population: Amiodarone induced Pulmonary Toxicity (n=1). Intervention: Amiodarone. Primary outcome: Clinical recovery from amiodarone-induced pulmonary toxicity.

December 1, 2012

Severe amiodarone induced pulmonary toxicity.

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Key result

A 63-year-old male with severe amiodarone-induced pulmonary toxicity was successfully managed with drug discontinuation and pulse high-dose steroid therapy.

Population

1 63-year-old male with non-ischemic cardiomyopathy, recurrent ventricular tachycardia, paroxysmal atrial…

Design

Case_report

Authors

NNNicholas Nacca CBCastigliano M. Bhamidipati LYLuke Yuhico

Discussion

Member takes

Overview

May support steroids after amiodarone discontinuation in severe toxicity; leaves open confirmation in controlled studies.

Study Design

Type

Case Report (n=1)

Multicenter

Structured PICO

Population

A 63-year-old male with non-ischemic cardiomyopathy and recurrent ventricular tachycardia who developed severe amiodarone-induced pulmonary toxicity.

Exposure

Discontinuation of amiodarone and initiation of pulse high-dose steroid therapy (1,000 mg/day for three consecutive days).

Outcome

Clinical improvement and liberation from mechanical ventilatory support.safety

Severe amiodarone-induced pulmonary toxicity can present as acute respiratory failure but may be successfully managed with prompt drug discontinuation and high-dose corticosteroid therapy.

Cite This Study

Nacca et al. (2012) conducted a case report in Amiodarone induced Pulmonary Toxicity (n=1). Amiodarone was evaluated on Clinical recovery from amiodarone-induced pulmonary toxicity. A 63-year-old male with severe amiodarone-induced pulmonary toxicity was successfully managed with drug discontinuation and pulse high-dose steroid therapy.

synapsesocial.com/papers/6a75dcb2030f9eaaaae6971f https://doi.org/10.3978/j.issn.2072-1439.2012.06.08

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December 1, 2012

Severe amiodarone induced pulmonary toxicity.

View Full Paper

Ask AI

Bookmark

Key result

A 63-year-old male with severe amiodarone-induced pulmonary toxicity was successfully managed with drug discontinuation and pulse high-dose steroid therapy.

Population

1 63-year-old male with non-ischemic cardiomyopathy, recurrent ventricular tachycardia, paroxysmal atrial…

Design

Case_report

Authors

NNNicholas Nacca CBCastigliano M. Bhamidipati LYLuke Yuhico

Discussion

Member takes

Overview

May support steroids after amiodarone discontinuation in severe toxicity; leaves open confirmation in controlled studies.

Study Design

Type

Case Report (n=1)

Multicenter

Structured PICO

Population

A 63-year-old male with non-ischemic cardiomyopathy and recurrent ventricular tachycardia who developed severe amiodarone-induced pulmonary toxicity.

Exposure

Discontinuation of amiodarone and initiation of pulse high-dose steroid therapy (1,000 mg/day for three consecutive days).

Outcome

Clinical improvement and liberation from mechanical ventilatory support.safety

Severe amiodarone-induced pulmonary toxicity can present as acute respiratory failure but may be successfully managed with prompt drug discontinuation and high-dose corticosteroid therapy.

Cite This Study

synapsesocial.com/papers/6a75dcb2030f9eaaaae6971f https://doi.org/10.3978/j.issn.2072-1439.2012.06.08

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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