Why the study?
Do baseline inflammatory cytokines predict mortality in adult patients with acute heart failure and/or acute coronary syndrome?
Population
75 adult patients with acute heart failure and/or acute coronary syndrome, mean age 65.5, 60.5% male, from a…
Design
Cohort
Follow-up
six months
Key result
Elevated baseline serum IL-6 is a strong independent predictor of overall mortality in patients following acute heart failure and/or acute coronary syndrome (HR 61.7).
Authors
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May refine post-acute HF/ACS risk stratification; leaves open whether IL-6 targeting improves outcomes.
Cohort (n=75)
No
Do baseline inflammatory cytokines predict mortality in adult patients with acute heart failure and/or acute coronary syndrome?
Hazard Ratio: 61.7 (95% CI 2.1–1851)
p-value: p=0.018
Elevated baseline serum IL-6 is a strong independent predictor of overall mortality in patients hospitalized for acute heart failure and/or acute coronary syndrome.
Aida Hamzić-Mehmedbašić (2016) conducted a cohort in Acute heart failure and/or acute coronary syndrome (n=75). Serum IL-6 vs. Lower levels (continuous variable) was evaluated on Overall mortality (in-hospital and six-month) (HR 61.7, 95% CI 2.1-1851.0, p=0.018). Elevated baseline serum IL-6 is a strong independent predictor of overall mortality in patients following acute heart failure and/or acute coronary syndrome (HR 61.7).