January 15, 2020Journal of Clinical HypertensionOpen Access

Noninvasive central pulse pressure is an independent determinant of renal function

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Why the study?

The study was conducted to investigate the prognostic properties of different BP measurements for renal function decrement and early chronic kidney disease in community-dwelling populations with normal baseline renal function.

Structured PICO

Population

1,426 community-dwelling adults in Beijing, China, without clinically apparent cardiovascular disease and with normal renal function (eGFR ≥60 mL/min per 1.73 m2) at baseline. Mean age 61.3 years, 57.4% female.

Outcome

Rapid eGFR decline (defined as a decline in eGFR of greater than 3 mL/min per 1.73 m2 per year) and new incidence of CKD (defined as a decrease in eGFR of 20% or more and to a level below 60 mL/min per 1.73 m2) at a median follow-up of 4.8 years.surrogate

Noninvasive central pulse pressure is an independent predictor of rapid renal function decline and incident chronic kidney disease in community-dwelling adults.

Discussion

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Implication

Central BP may refine early CKD risk prediction beyond brachial measures; leaves open whether it alters management in normotensive adults.

Cite This Study

Xiao et al. (2020) studied this question.

synapsesocial.com/papers/6a75f630f1e99ff85ab226f3 https://doi.org/10.1111/jch.13792

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Implication

Central BP may refine early CKD risk prediction beyond brachial measures; leaves open whether it alters management in normotensive adults.

Noninvasive central pulse pressure is an independent determinant of renal function

Structured PICO

Discussion

Implication

Cite This Study

Noninvasive central pulse pressure is an independent determinant of renal function

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider