Why the study?
Does propranolol prevent attacks in patients with ventricular tachyarrhythmia?
Does propranolol prevent attacks in patients with ventricular tachyarrhythmia?
Long-term prophylactic treatment with propranolol may be effective in reducing the frequency of ventricular tachyarrhythmia attacks in both adults and children, though adverse effects like bradycardia and thrombocytopenia can occur.
Answers are grounded in this paper and cite their sources.
May support propranolol in select refractory cases; leaves open efficacy confirmation in randomized trials.
The results of prophylactic treatment for more than 2 1/2 years with propranolol in four patients with attacks of ventricular tachyarrhythmia are reported. Two of the patients are children. Good results were obtained in three of the patients, who lead a satisfactory life with no or rare attacks of tachycardia. In one patient the treatment has only decreased the frequency of the severe attacks somewhat. The growth and development of the two children have been normal. In one patient more pronounced bradycardia with drowsiness has been encountered, as well as symptomless thrombocytopenia. In another patient the medical treatment had to be supplemented by a pacemaker.
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Wennevold et al. (1968) studied this question.
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