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November 1, 1989The Journal of Infectious Diseases

Rotavirus-Specific Cytotoxic T Lymphocyte Response of Mice after Oral Inoculation with Candidate Rotavirus Vaccine Strains RRV or WC3

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Authors

POPaul A. OffitChildren's Hospital of Philadelphia YSYasmine M. SvobodaThe Wistar Institute

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Implication

Strain-specific CTL responses in mice warrant no clinical vaccine changes; leaves open human heterotypic protection mechanisms.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Offit et al. (1989) studied this question.

synapsesocial.com/papers/6a7621700327049ca48c5d3a https://doi.org/10.1093/infdis/160.5.783

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Response of mice to rotaviruses of bovine or primate origin assessed by radioimmunoassay, radioimmunoprecipitation, and plaque reduction neutralization1983 · 66 citations
2Protective Effect of WC3 Vaccine Against Rotavirus Diarrhea in Infants During a Predominantly Serotype 1 Rotavirus Season1988 · 243 citations
3Avirulent Rotavirus Infections Protect Calves from Disease with and without Inducing High Levels of Neutralizing Antibody1987 · 50 citations
4Candidate Rotavirus Vaccine (Rhesus Rotavirus Strain) in Children: An Evaluation1987 · 39 citations
5Serotypic Similarity and Diversity of Rotaviruses of Mammalian and Avian Origin as Studied by Plaque-Reduction Neutralization1984 · 420 citations