What question did this study set out to answer?

To evaluate gender-specific clinical and echocardiographic characteristics and assess their relationship to mortality outcomes among hospitalized heart failure patients.

February 19, 2013European Journal of Heart Failure

Gender-Related Differences in Hospitalized Heart Failure Patients

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Why the study?

Are there gender-specific differences in clinical characteristics and predictors of mortality among hospitalized heart failure patients?

Key Points

To evaluate gender-specific clinical and echocardiographic characteristics and assess their relationship to mortality outcomes among hospitalized heart failure patients.
Analyzed 9,335 consecutive patients aged 50 or older (5,228 males and 4,107 females) hospitalized with heart failure between January 2000 and December 2009 who had at least one echocardiography study.
Evaluated clinical and echocardiographic features across genders with a mean follow-up of 2.8 ± 2.6 years.
Females had higher rates of hypertension, atrial fibrillation, obesity, valvular abnormalities, and pulmonary hypertension, whereas males had higher rates of ischemic heart disease, stroke, chronic renal failure, and COPD.
Unadjusted 30-day and 1-year mortality rates were higher among women, but age-adjusted mortality rates were similar between males and females.
Predictors of mortality differed significantly by sex: aortic stenosis, pulmonary hypertension, and malignancy predicted female mortality, while diastolic dysfunction and chronic renal failure were male-specific predictors.

Structured PICO

Are there gender-specific differences in clinical characteristics and predictors of mortality among hospitalized heart failure patients?

Population

9,335 consecutive heart failure patients (5,228 males and 4,107 females), aged 50 or older, hospitalized between January 2000 and December 2009, who had undergone at least one echocardiography study.

Intervention

Female gender

Comparator

Male gender

Outcome

30-day and 1-year mortality, and predictors of mortalityhard clinical

While age-adjusted mortality rates are similar between male and female hospitalized heart failure patients, the clinical predictors of mortality differ significantly by gender.

Discussion

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Implication

Sex-specific mortality predictors in hospitalized HF warrant attention; leaves open whether targeted strategies improve outcomes.

Cite This Study

Stein et al. (2013) studied this question.

synapsesocial.com/papers/6a762976d01cd5d9a1707b6f https://doi.org/10.1093/eurjhf/hft024

Topics

HFrEF treatment Heart failure Women and heart disease Heart failure hospitalization

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Gender-Related Differences in Hospitalized Heart Failure Patients

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Topics

Gender-Related Differences in Hospitalized Heart Failure Patients

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

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