Why the study?
Does streptokinase lyse platelet masses in an artificial in vitro thrombosis model?
Population
Artificial in vitro thrombosis model produced using a cone-in-cone rotational viscometer
Design
Preclinical
Authors
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May reduce streptokinase efficacy in platelet-rich thrombi; leaves open need for adjunctive antiplatelet strategies in future studies.
Does streptokinase lyse platelet masses in an artificial in vitro thrombosis model?
In an in vitro thrombosis model, streptokinase lyses coagula but fails to affect platelet masses, which has implications for thrombolytic therapy.
M. C. Rozenberg (1965) studied this question.
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