Why the study?
Is large mean platelet volume associated with high residual platelet reactivity after aspirin and clopidogrel therapy in patients undergoing PCI?
Population
462 consecutive patients with coronary artery disease scheduled to undergo planned percutaneous coronary…
Comparison
Large platelets while on dual antiplatelet… vs Smaller platelets while on dual antiplatelet…
Design
Cohort
Authors
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Large platelets should not yet guide DAPT post-PCI; leaves open utility for risk stratification or outcome prediction.
Is large mean platelet volume associated with high residual platelet reactivity after aspirin and clopidogrel therapy in patients undergoing PCI?
In patients undergoing PCI, larger mean platelet volume is associated with higher residual platelet reactivity on standard dual antiplatelet therapy, though this did not translate to differences in major adverse cardiac events.
Kim et al. (2014) studied this question.
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