March 1, 1989Annual Review of Physiology

Ca2+ Crossbridge Phosphorylation, and Contraction

View Full Paper

Ask AI

Bookmark

Population

Smooth muscle

Design

Review

Authors

CHChi-Ming HaiBrown University RMRichard A. MurphyUniversity of Southern California

Discussion

Member takes

Implication

MLCK activation may not fully explain smooth muscle dynamics; leaves open complementary regulatory pathways for mechanistic study.

Structured PICO

Population

Smooth muscle

Intervention

Ca2+-calmodulin dependent myosin light chain kinase (MLCK) activation

Outcome

Steady-state and transient changes in crossbridge phosphorylation, isometric stress, and isotonic shortening velocity

This review discusses whether Ca2+-calmodulin dependent MLCK activation can explain changes in crossbridge phosphorylation and contraction mechanics in smooth muscle.

Cite This Study

Hai et al. (1989) studied this question.

synapsesocial.com/papers/6a766dbeda34852ffa95c5aa https://doi.org/10.1146/annurev.ph.51.030189.001441

View Full Paper

Ask AI

Bookmark

Ca2+ Crossbridge Phosphorylation, and Contraction

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Ca2+ Crossbridge Phosphorylation, and Contraction

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider