Why the study?
What are the clinical characteristics and outcomes of patients who develop endocarditis despite antimicrobial prophylaxis?
Population
52 patients with apparent endocarditis prophylaxis failure reported to an American Heart Association…
Design
Case_series
Authors
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Prophylaxis failures occur despite susceptible organisms; case-level data leave open the protective effect of AHA-recommended regimens.
What are the clinical characteristics and outcomes of patients who develop endocarditis despite antimicrobial prophylaxis?
Endocarditis prophylaxis failures occur even with susceptible organisms, though most patients in this registry did not receive AHA-recommended regimens.
David T. Durack (1983) studied this question.
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