Why the study?
How do various levels of mean pulmonary blood flow affect transpulmonary circulatory transport functions in anesthetized dogs?
Population
four anesthetized dogs
Design
Preclinical
Authors
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Increases in canine lung dispersion with transit time support parallel-pathway perfusion model; leaves open human applicability.
How do various levels of mean pulmonary blood flow affect transpulmonary circulatory transport functions in anesthetized dogs?
In a canine model, the relative dispersion of lung transport functions increases with mean transit time, suggesting the lung acts as a parallel-pathway system where pathways become more equally perfused at higher flows.
Knopp et al. (1969) studied this question.
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