Why the study?
Does desmopressin (DDAVP) reduce bleeding time in patients treated with heparin for acute venous thromboembolism?
Population
20 patients treated for acute venous thromboembolism
Comparison
Heparin followed by an infusion with… vs Heparin followed by placebo
Design
RCT, randomized, double-blind
Authors
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May support DDAVP for heparin-related bleeding complications; extends RCT evidence to acute VTE patients.
Does desmopressin (DDAVP) reduce bleeding time in patients treated with heparin for acute venous thromboembolism?
Desmopressin (DDAVP) partially reverses the prolongation of bleeding time induced by heparin, suggesting it may be useful for managing heparin-associated hemorrhagic complications.
Schulman et al. (1991) studied this question.
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