December 1, 1991AJP Endocrinology and Metabolism

Ethnic differences in sympathetic nervous system-mediated energy expenditure

View Full Paper

Ask AI

Bookmark

Why the study?

Does sympathetic nervous system activity impact energy expenditure differently in Caucasian versus Pima Indian men?

Population

69 nondiabetic men on a weight-maintenance diet, comprising 36 Caucasians and 33 Pima Indians in Study 1…

Comparison

Propranolol infusion to evaluate… vs Baseline resting metabolic rate and comparison…

Design

Cross-sectional

Authors

MSMohammad F. SaadSharda University SASharon AlgerNational Institutes of Health FZF. ZurloUniversity of Padua

Discussion

Member takes

Implication

Ethnic differences in SNS-energy expenditure links warrant caution generalizing across groups; leaves open mechanisms of obesity predisposition.

Structured PICO

Does sympathetic nervous system activity impact energy expenditure differently in Caucasian versus Pima Indian men?

Population

69 nondiabetic men on a weight-maintenance diet, comprising 36 Caucasians (mean age 32, 95 kg, 22% fat) and 33 Pima Indians (mean age 29, 103 kg, 30% fat) in Study 1; and 68 men (36 Caucasians, 32 Pimas) in Study 2.

Intervention

Propranolol infusion (120 micrograms/kg fat-free mass bolus and 1.2 micrograms/kg fat-free mass/min for 45 min) to evaluate beta-adrenoceptor blockade effect on resting metabolic rate.

Comparator

Baseline resting metabolic rate (prior to propranolol infusion) and comparison between Caucasian and Pima Indian ethnic groups.

Outcome

Relationship between 24-h energy expenditure and 24-h urinary norepinephrine, and the effect of propranolol on resting metabolic rate.surrogate

Sympathetic nervous system activity is significantly correlated with energy expenditure in Caucasian men but not in Pima Indian men, suggesting ethnic differences in metabolic regulation.

Cite This Study

Saad et al. (1991) studied this question.

synapsesocial.com/papers/6a768cec3e7bb358cacfef3a https://doi.org/10.1152/ajpendo.1991.261.6.e789

View Full Paper

Ask AI

Bookmark

Implication

Ethnic differences in SNS-energy expenditure links warrant caution generalizing across groups; leaves open mechanisms of obesity predisposition.

Ethnic differences in sympathetic nervous system-mediated energy expenditure

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Ethnic differences in sympathetic nervous system-mediated energy expenditure

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider