Why the study?
To explore whether a sigmoid-shaped interventricular septum affects left ventricular systolic function in patients with hypertension using two-dimensional speckle tracking echocardiography.
Does the presence of a sigmoid-shaped interventricular septum affect left ventricular systolic function in patients with essential hypertension as evaluated by 2D-STE?
Does the presence of a sigmoid-shaped interventricular septum affect left ventricular systolic function in patients with essential hypertension as evaluated by 2D-STE?
Sigmoid-shaped interventricular septum is associated with reduced regional left ventricular systolic function in hypertensive patients, which can be detected early using 2D speckle tracking echocardiography.
Answers are grounded in this paper and cite their sources.
SIS may impair regional LV systolic function in hypertension; leaves open need for larger studies before clinical adoption.
Objective: To evaluate left ventricular regional and global systolic function by measuring left ventricular longitudinal strain (LS) in hypertensive patients with sigmoid-shaped interventricular septum (SIS) by two-dimensional speckle tracking (2D-STE); in order to explore whether the sigmoid-shaped interventricular septum affects the left ventricular systolic function in patients with hypertension. Methods: Routine echocardiographic parameters were measured in 30 hypertensive patients with SIS (SIS group) and 30 hypertensive patients without SIS (non-SIS group). The left ventricular segments and global LS were measured by 2D-STE, and the two sets of parameters were compared. Results: The value of the thickness of the basal segment of the interventricular septum (IVSBT), the thickness of the middle segment of the interventricular septum (IVSMT) and the ratio of the basal segment of the ventricular septum to the middle segment of the interventricular septum (IVSBT/IVSMT) in SIS group was higher than that in non-SIS group. However, the value of left ventricular outflow tract diameter (LVOTD) in SIS group was lower than that in non-SIS group. There was a significant difference between the two groups (all P < 0 05). The LS values of the basal segment of the left ventricular anterior wall and the posterior wall of the left ventricle in the SIS group were lower than those in the non-SIS group. The difference was statistically significant (all P < 0.05). Conclusion: SIS affects left ventricular regional systolic function of patients with hypertension. 2D-STE can early evaluate left ventricular longitudinal systolic function in hypertensive patients with SIS.
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Zhang et al. (2019) studied this question.
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