Key result
Hypertensive patients with left ventricular hypertrophy had significantly reduced global longitudinal left ventricular systolic strain compared to hypertensive patients without hypertrophy (P=0.04).
Why the study?
Does two-dimensional speckle tracking echocardiography detect differences in LV longitudinal strain and strain rate between hypertensive patients with and without LVH compared to controls?
Population
75 subjects including 50 patients with hypertension and 25 age- and sex-matched controls.
Comparison
Two-dimensional speckle tracking… vs Comparison between hypertensive patients with…
Design
Cross-sectional
Authors
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Strain reduction in hypertensive LVH may indicate subclinical dysfunction; hypothesis-generating and requires prospective validation before clinical adoption.
Observational (n=75)
Does two-dimensional speckle tracking echocardiography detect differences in LV longitudinal strain and strain rate between hypertensive patients with and without LVH compared to controls?
p-value: p=0.04
Speckle-tracking echocardiography reveals substantial impairment of LV systolic and diastolic function in hypertensive patients, which is more pronounced in those with left ventricular hypertrophy.
Braik et al. (2014) conducted an observational in Hypertension (n=75). Hypertension with left ventricular hypertrophy vs. Hypertension without left ventricular hypertrophy and healthy controls was evaluated on Global longitudinal LV systolic strain (p=0.04). Hypertensive patients with left ventricular hypertrophy had significantly reduced global longitudinal left ventricular systolic strain compared to hypertensive patients without hypertrophy (P=0.04).
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