What question did this study set out to answer?

To evaluate the acute effects of right ventricular septal pacing compared with apical pacing on left ventricular dyssynchrony and global longitudinal function using speckle tracking echocardiography.

January 1, 2011Circulation JournalOpen Access

Right Ventricular Septal Pacing Preserves Global Left Ventricular Longitudinal Function in Comparison With Apical Pacing - Analysis of Speckle Tracking Echocardiography -

View Full Paper

Ask AI

Bookmark

Why the study?

Does right ventricular septal pacing improve LV dyssynchrony and longitudinal function compared to apical pacing in patients with symptomatic bradyarrhythmia?

Population

103 patients with symptomatic bradyarrhythmia and preserved LV ejection fraction, and 50 age-matched control…

Comparison

Right ventricular septal pacing (RVS) vs Right ventricular apical pacing and age-matched…

Design

RCT, randomly assigned into 2 groups

Follow-up

acute (during RV pacing after insertion)

Authors

KIKatsuji InouePulmonary Hypertension Association HOHideki OkayamaInterventional / Structural Cardiology KNKazuhisa NishimuraCardiac Imaging

Discussion

Member takes

Implication

Supports right ventricular septal over apical pacing to preserve LV longitudinal strain; extends RCT evidence for alternative sites in symptomatic bradyarrhythmia.

Key Points

To evaluate the acute effects of right ventricular septal pacing compared with apical pacing on left ventricular dyssynchrony and global longitudinal function using speckle tracking echocardiography.
Randomized trial including 103 patients (mean age 74 ± 9 years) with symptomatic bradyarrhythmia and preserved left ventricular ejection fraction randomly assigned to apical pacing (n = 51) or septal pacing (n = 52), alongside 50 age-matched controls.
Speckle tracking echocardiography was performed after pacemaker implantation during ventricular pacing to evaluate QRS width, dyssynchrony indices, and global strain parameters.
Global longitudinal strain was significantly more preserved with septal pacing (-16.8 ± 2.7%) than apical pacing (-14.3 ± 3.1%, P < 0.01), while controls measured -18.2 ± 2.4% (P < 0.001 vs. apical pacing).
Apical pacing resulted in significantly wider QRS durations and higher longitudinal and radial dyssynchrony indices compared with both septal pacing and control groups.
Left ventricular longitudinal dyssynchrony was significantly correlated with impaired global longitudinal strain across all 103 paced patients (R² = 0.25, P < 0.0001).

Structured PICO

Does right ventricular septal pacing improve LV dyssynchrony and longitudinal function compared to apical pacing in patients with symptomatic bradyarrhythmia?

Population

103 patients (749 years) with symptomatic bradyarrhythmia and preserved LV ejection fraction, and 50 age-matched control subjects

Intervention

Right ventricular septal pacing (RVS)

Comparator

Right ventricular apical pacing (RVA) and age-matched controls

Outcome

LV dyssynchrony and global strain parameters (including global longitudinal strain) measured by speckle tracking echocardiographysurrogate

Right ventricular septal pacing preserves global left ventricular longitudinal function and reduces dyssynchrony compared to apical pacing in patients with symptomatic bradyarrhythmia.

Cite This Study

Inoue et al. (2011) studied this question.

synapsesocial.com/papers/6a7699d44c326aeb7c060d7e https://doi.org/10.1253/circj.cj-10-1138

Topics

Echocardiography

View Full Paper

Ask AI

Bookmark

Implication

Supports right ventricular septal over apical pacing to preserve LV longitudinal strain; extends RCT evidence for alternative sites in symptomatic bradyarrhythmia.

Right Ventricular Septal Pacing Preserves Global Left Ventricular Longitudinal Function in Comparison With Apical Pacing - Analysis of Speckle Tracking Echocardiography -

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Right Ventricular Septal Pacing Preserves Global Left Ventricular Longitudinal Function in Comparison With Apical Pacing - Analysis of Speckle Tracking Echocardiography -

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider