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July 1, 1977Clinical Science

The Assessment of Left Ventricular Ejection Fraction in Patients with Ischaemic Heart Disease by Contrast Ventriculography and Nuclear Angiography

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Why the study?

Do nuclear angiographic methods accurately measure left ventricular ejection fraction compared to contrast ventriculography in patients with ischaemic heart disease?

Population

18 patients with ischaemic heart disease

Comparison

Two nuclear angiographic methods vs Single-plane contrast angiography

Design

Cross-sectional

Authors

AMAlexander MuirUniversity of ChicagoWHW. J. HannanJohn Brown UniversityHBH. M. BrashUniversity of Edinburgh

Discussion

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Overview

Supports gated nuclear angiography for non-invasive LVEF assessment in ischaemic heart disease; leaves open prospective validation.

Structured PICO

Do nuclear angiographic methods accurately measure left ventricular ejection fraction compared to contrast ventriculography in patients with ischaemic heart disease?

P
Population
18 patients with ischaemic heart disease
I
Intervention
Two nuclear angiographic methods (bolus method using 99Tcm-labelled human serum albumin and a modified 'gated' method)
C
Comparator
Single-plane contrast angiography
O
Outcome
Left ventricular ejection fractionsurrogate

A modified gated nuclear angiography method provides a useful non-invasive means for assessing left ventricular function, correlating well with contrast ventriculography.

Cite This Study

Muir et al. (1977) studied this question.

synapsesocial.com/papers/6a76d06fd8eb58afc2bd6cd6https://doi.org/10.1042/cs0530055
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of Left Ventricular Ejection Fraction Assessed by Radionuclide Angiocardiography, Echocardiography and Contrast Angiocardiography1982 · 11 citations
  2. 2Nontraumatic determination of left ventricular ejection fraction by radionuclide angiocardiography.1975 · 192 citations
  3. 3Comparison of left ventricular ejection fraction values obtained using invasive contrast left ventriculography, two-dimensional echocardiography, and gated single-photon emission computed tomography2016 · 11 citations
  4. 4Comparison of radionuclide ventriculography and 2D echocardiography for the measurement of left ventricular ejection fraction following acute myocardial infarction1994 · 44 citations
  5. 5Assessment of left ventricular ejection fraction from technetium-99m-methoxy isobutyl isonitrile multiple-gated radionuclide angiocardiography1993 · 8 citations