Why the study?
Helical CT and transesophageal echocardiography are not feasible for every suspected case of acute aortic dissection, and research on D-dimer to rule out the condition has been limited by its rarity.
Does D-dimer testing accurately rule out acute aortic dissection in suspected patients?
Population
1,319 patients with confirmed AAD and D-dimer testing within a day of diagnosis
Comparison
D-dimer cutoff of 400 ng/ml vs 500 ng/ml
Design
Retrospective cohort study
Authors
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D-dimer testing is highly sensitive (up to 94.9%) for acute aortic dissection and can serve as a reliable rule-out tool to avoid invasive imaging in low-risk patients.
Does D-dimer testing accurately rule out acute aortic dissection in suspected patients?
D-dimer testing is highly sensitive (up to 94.9%) for acute aortic dissection and can serve as a reliable rule-out tool to avoid invasive imaging in low-risk patients.
Carter et al. (2023) studied this question.
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