Population
tsA201 cells
Comparison
Expression of skeletal beta1a or cardiac beta2a… vs Expression of alpha1S alone, or comparison…
Design
Preclinical
Authors
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Differential beta localization may shape channel trafficking in heterologous cells; leaves open relevance to native skeletal or cardiac muscle.
The study demonstrates that skeletal beta1a and cardiac beta2a subunits differentially regulate the subcellular localization and current expression of the alpha1S Ca2+ channel subunit in tsA201 cells.
Neuhuber et al. (1998) studied this question.
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