Population
Patients with adult respiratory distress syndrome, chronic obstructive lung disease, cardiogenic pulmonary…
Design
Cross-sectional
Authors
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Serum NEP may mark endothelial damage in ARDS and edema; hypothesis-generating for biomarker use, requiring prospective validation.
Serum neutral metalloendopeptidase (NEP) is markedly elevated in ARDS and cardiogenic pulmonary edema, suggesting it may serve as a biomarker for endothelial damage or leukocyte release in these conditions.
Johnson et al. (1985) studied this question.
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