Why the study?
Does a low sodium diet enhance the aldosterone-stimulating activity of angiotensin II in dogs?
Population
Dogs fed a low sodium diet for 14 days and control dogs
Comparison
Various doses of angiotensin II vs Control dogs receiving angiotensin II
Design
Preclinical
Follow-up
14 days
Authors
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Low-sodium diet may potentiate angiotensin II effects on aldosterone in dogs; leaves open human relevance and requires clinical validation.
Does a low sodium diet enhance the aldosterone-stimulating activity of angiotensin II in dogs?
A low sodium diet enhances the aldosterone-stimulating effect of angiotensin II in dogs without affecting 17-hydroxycorticoids or blood pressure.
Ganong et al. (1967) studied this question.
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