Key result
Mean platelet volume was significantly higher in patients with cardiac chest pain compared to those with non-cardiac chest pain (mean difference 0.89, p<0.001).
Why the study?
To investigate the efficacy of mean platelet volume and platelet/MPV ratio as markers for the differential diagnosis of acute coronary syndrome vs non-cardiac chest pain and for predicting critical vascular stenosis.
Does MPV and platelet/MPV ratio differentiate cardiac from non-cardiac chest pain and predict severity in patients presenting to the ED with chest pain?
Observational (n=753)
No
Does MPV and platelet/MPV ratio differentiate cardiac from non-cardiac chest pain and predict severity in patients presenting to the ED with chest pain?
Elevated MPV and decreased platelet/MPV ratio are associated with cardiac chest pain and critical coronary stenosis, but have low sensitivity and specificity for routine standalone diagnostic use.
Higher MPV may associate with cardiac chest pain; hypothesis-generating and should not yet change practice.
ÖZ GİRİŞ ve AMAÇ: Acil servise başvuran hastalarda akut koroner sendrom ve kardiyak / kardiyak olmayan göğüs ağrısının ayırıcı tanısı ile kritik vaskuler stenozun öngörülmesinde mortalite üzerine bağımsız bir belirteç olarak mean platelet volum (MPV) ve trombosit / MPV oranının etkinliğini araştırmak. YÖNTEM ve GEREÇLER: Retrospektif gözlemsel çalışmaya göğüs ağrısı ile acil servise başvuran 45 yaş ve üstü hastalar dahil edildi. Hastalar kardiyak / kardiyak olmayan göğüs ağrısı olarak gruplara ayrıldı. MPV, trombosit/ MPV oranı, koroner anjiyografi sonuçları, hastane içi ve 1 aylık hastane
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Karakayalı et al. (2019) conducted an observational in Chest pain (cardiac vs non-cardiac) (n=753). Mean platelet volume (MPV) and platelet/MPV ratio vs. Non-cardiac chest pain was evaluated on Mean platelet volume (MPV) in cardiac vs non-cardiac chest pain (MD 0.89, 95% CI 0.70-1.07, p=<0.001). Mean platelet volume was significantly higher in patients with cardiac chest pain compared to those with non-cardiac chest pain (mean difference 0.89, p<0.001).
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