Why the study?
Does autonomic neuropathy impair counterregulatory catecholamine responses and awareness of hypoglycemia in type 1 diabetic patients?
Population
55 subjects total: 22 type 1 diabetic patients matched for age, duration of diabetes, glycemic control, and…
Comparison
Presence of autonomic neuropathy (AN+) vs Absence of autonomic neuropathy and nondiabetic…
Design
Cross-sectional
Authors
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May increase severe hypoglycemia risk in T1D with autonomic neuropathy; hypothesis-generating and requires prospective confirmation.
Does autonomic neuropathy impair counterregulatory catecholamine responses and awareness of hypoglycemia in type 1 diabetic patients?
Autonomic neuropathy in type 1 diabetes further reduces counterregulatory catecholamine responses to hypoglycemia, increasing the risk for severe hypoglycemia.
Meyer et al. (1998) studied this question.
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