Population
Type I diabetic patients
Design
Review
Authors
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May caution against intensive insulin in hypoglycemia unawareness; leaves open neuropathy subtype effects on counterregulation.
Patients with recurrent hypoglycemia unawareness or a history of hypoglycemia-related accidents should probably not be treated with intensive insulin therapy until glucose counterregulation is more fully understood.
Robert D. Hoeldtke (1994) studied this question.
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