Why the study?
Does diabetic autonomic neuropathy affect epinephrine secretion and hypoglycemia awareness during insulin-induced hypoglycemia?
Population
27 individuals: 18 diabetic patients (9 with autonomic neuropathy, 9 without) and 9 normal volunteers.
Comparison
Insulin-induced hypoglycemia vs Normal volunteers and diabetic patients without…
Design
Cross-sectional
Authors
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May increase severe hypoglycemia risk via unawareness; hypothesis-generating and requires prospective validation before guiding practice.
Does diabetic autonomic neuropathy affect epinephrine secretion and hypoglycemia awareness during insulin-induced hypoglycemia?
Diabetic autonomic neuropathy is associated with impaired epinephrine secretion, leading to hypoglycemia unawareness and increased risk of severe hypoglycemia.
Robert D. Hoeldtke (1982) studied this question.
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