Why the study?
Do orally administered bronchodilators (ephedrine, aminophylline, terbutaline) cause arrhythmogenic effects in patients with pre-existing ventricular arrhythmia?
Population
20 patients with ventricular arrhythmia
Comparison
Orally administered ephedrine sulfate 25 mg… vs Placebo
Design
RCT, double-blind
Follow-up
four hours
Authors
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Terbutaline warrants caution in patients with ventricular arrhythmias; confirms greater arrhythmogenicity than ephedrine or aminophylline.
Do orally administered bronchodilators (ephedrine, aminophylline, terbutaline) cause arrhythmogenic effects in patients with pre-existing ventricular arrhythmia?
Orally administered terbutaline increases ventricular ectopic beats and can induce ventricular tachycardia in patients with pre-existing arrhythmias, indicating it is not safer than ephedrine or aminophylline.
Alberta Banner (1979) studied this question.
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