Key result
Terbutaline sulfate linked to ~100% increased cardiac output, elevated heart rate, and incident PVCs.
Why the study?
Terbutaline, thought to have negligible cardiovascular effects due to β2 selectivity, has been found to increase heart rate and cardiac output, raising concerns about arrhythmias.
Does terbutaline cause adverse cardiovascular effects such as arrhythmias?
Population
Patients receiving terbutaline including asthmatics
Design
Letter to the editor
Authors
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Terbutaline increases heart rate; leaves open its relative cardiovascular safety versus β1 agents in asthma.
Does terbutaline cause adverse cardiovascular effects such as arrhythmias?
Despite its relative beta-2 receptor selectivity, terbutaline can cause significant cardiovascular effects including increased heart rate, cardiac output, and arrhythmias.
Evlin L. Kinney (1978) reported a letter. Terbutaline sulfate was evaluated. Terbutaline sulfate has been associated with increased heart rate, doubled cardiac output, and the onset of premature ventricular contractions.
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