Why the study?
Does endogenous renin and angiotensin II mediate the increase in plasma angiotensinogen after nephrectomy in rats?
Does endogenous renin and angiotensin II mediate the increase in plasma angiotensinogen after nephrectomy in rats?
Endogenous angiotensin II, acting via AT1 receptors, is the primary mediator of the increase in hepatic angiotensinogen synthesis following bilateral nephrectomy in rats.
No takes yet. Share an insight, caveat, or question.
AT1 blockade prevents post-nephrectomy angiotensinogen rise in rats; leaves open translation to human physiology or practice.
Hilgenfeldt et al. (1993) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: