Why the study?
Does angiotensin II facilitate noradrenaline release at postganglionic sympathetic terminal axons in anesthetized rabbits?
Population
Anesthetized rabbits (alfadolone + alfaxalone)
Comparison
Angiotensin II infusion for 4 minutes… vs Basal values (before infusion) and controls
Design
Preclinical
Follow-up
4 minutes
Authors
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Exogenous angiotensin II may facilitate noradrenaline release per impulse in rabbits; leaves open relevance of endogenous angiotensin II to human sympathetic regulation.
Does angiotensin II facilitate noradrenaline release at postganglionic sympathetic terminal axons in anesthetized rabbits?
Exogenous angiotensin II facilitates noradrenaline release from postganglionic sympathetic neurons in rabbits, though endogenous angiotensin II does not appear to regulate cardiovascular function under acute experimental conditions.
Szabó et al. (1990) studied this question.
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