Population
Aspirinated human platelets labeled with 32PO4
Comparison
ADP stimulation vs Ionomycin stimulation or unstimulated state
Design
Preclinical
Authors
Loading...
Extends ADP-IP3 signaling data in aspirinated platelets; leaves open in vivo relevance and clinical translation.
ADP stimulates human platelets via IP3 formation to liberate internal Ca2+, a mechanism similar to other platelet agonists.
Daniel et al. (1986) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: