Why the study?
Does isoproterenol improve cardiac energetics and function in Syrian cardiomyopathic hamsters?
Population
Langendorff perfused hearts from Syrian cardiomyopathic hamsters (n=5) and normal hamsters
Comparison
10(-6)M infusion of isoproterenol vs Baseline and normal hamsters receiving the same…
Design
Preclinical
Authors
Loading...
Challenges energetic detriment assumption with inotropes; leaves open translation beyond this animal model.
Does isoproterenol improve cardiac energetics and function in Syrian cardiomyopathic hamsters?
Isoproterenol infusion improves myocardial performance and high-energy phosphate metabolites in Syrian cardiomyopathic hamsters, contrasting with the energetic deterioration seen in normal hamsters.
Camacho et al. (1988) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: