Why the study?
Do calcium channel blockers reduce cardiovascular events in hypertensive patients?
Population
Hypertensive patients (data from 10 RCTs: 6 trials with < 1500 patients, 4 trials with > 4500 patients)
Comparison
Calcium channel blockers as a class… vs Diuretics (in some trials)
Design
Systematic_review
Authors
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Long-acting CCBs merit first-line use in hypertension; confirms event reduction and diuretic equivalence in high-risk patients.
Do calcium channel blockers reduce cardiovascular events in hypertensive patients?
Long-acting calcium channel blockers are effective as first-line treatment for reducing cardiovascular events in hypertensive patients, including those with diabetes.
Leeuw et al. (2002) studied this question.
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