Why the study?
Does left ventricular hypertrophy in hypertensive patients impair coronary hemodynamics as measured by 13N-ammonium PET compared to healthy controls?
Population
53 individuals, comprising 38 patients with left ventricular hypertrophy in the presence of hypertensive…
Comparison
13N-ammonium positron emission tomography… vs Healthy controls without a history of…
Design
Case-control
Authors
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Impaired coronary reserve in hypertensive LVH may flag subclinical ischemia risk; hypothesis-generating for concentric geometry as a therapeutic target.
Does left ventricular hypertrophy in hypertensive patients impair coronary hemodynamics as measured by 13N-ammonium PET compared to healthy controls?
Patients with hypertensive left ventricular hypertrophy have impaired coronary flow reserve during vasodilation despite normal resting myocardial blood flow, particularly in those with concentric hypertrophy.
Рыжкова et al. (2005) studied this question.
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