Why the study?
Does blockade of the renin-angiotensin system in young spontaneously hypertensive rats reduce long-term blood pressure?
Population
Young spontaneously hypertensive rats (SHR)
Design
Review
Authors
Loading...
May support developmental BP programming in SHR models; leaves open translation to early RAS blockade in human hypertension.
Does blockade of the renin-angiotensin system in young spontaneously hypertensive rats reduce long-term blood pressure?
Early blockade of the renin-angiotensin system in spontaneously hypertensive rats may permanently lower blood pressure through a developmental genetic mechanism.
Stephen Harrap (1992) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: