Why the study?
Does selective intracoronary drug injection combined with a Walton strain gauge allow for localized measurement of myocardial contraction without generalized circulatory effects?
Population
Open-chest or closed-chest preparations (likely animal models)
Comparison
Selective coronary artery catheterization for… vs Non-injected areas of the heart
Design
Preclinical
Authors
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Provides a tool for localized myocardial studies in animals; leaves open clinical translation.
Does selective intracoronary drug injection combined with a Walton strain gauge allow for localized measurement of myocardial contraction without generalized circulatory effects?
Selective intracoronary drug injection combined with a strain gauge provides a method to study localized myocardial contraction without systemic confounding.
James W. West (1962) studied this question.
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